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A systematic search for relevant articles published until March 2019 was performed using the databases PubMed, EMBASE, and Web of Science

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The endothelium is the lining of blood vessels, and endothelial function controls how the blood vessels relax or contract to control blood pressure.[ref][ref] Related article: MTHFR, riboflavin, and reducing high blood pressure 4

3.4.4 Alkaloids: comprehensive miRNA biogenesis modulation Berberine targets multiple oncogenic miRNAs, including miR-21 (5070% reduction in HCT116 cells), miR-23a (2.5-fold increase in hepatoma cells), and suppression of the miR-1792 cluster in multiple myeloma

J Clin Endocrinol Metab 1971;33:1536

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