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Keywords: glutathione, mitochondria, cholesterol, reactive oxygen species, steatohepatitis, Alzheimer disease INTRODUCTION Glutathione (GSH), the major intracellular thiol compound, is a ubiquitous tripeptide produced by most mammalian cells and it is the main mechanism of antioxidant defense against reactive oxygen species (ROS) and electrophiles

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Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

By boosting 2,3-DPG and ATP production, the therapy improves oxygen release and energy within cells

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