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Focus has been particularly on registered agents (mostly used in clinics to manage Fe accumulation in transfusion-dependent anemias) with known pharmacokinetic and safety profiles

No large randomised controlled trials

1,4,33 It is important to note that individuals with emphysema may not have airflow limitations per spirometry but may still report respiratory symptoms or have identified structural or functional abnormalities

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doi: 10.1016/j.neurobiolaging.2018.02.024 306 GuYLiYWangJZhangLZhangJWangY

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