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First, in the public healthcare system, the mean age of tested individuals was 54 years

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According to the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) Obesity Clinical Practice Guidelines, weight loss medications should be offered as chronic treatment along with lifestyle modifications to patients with obesity when the potential benefits outweigh the risks

Mice tolerated doses several times higher than the effective dose with no observable adverse effects

[31] The products are usually extracted and purified by phenol-methylene chloride extraction or by column chromatography