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Chronic kidney disease alters intestinal microbial flora

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The high ROS environment lowers the activation threshold of mast cells, causing them to degranulate inappropriately and release a flood of inflammatory cytokines, including histamine, interleukins, and tumor necrosis factor-alpha (TNF-a)

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Epigenetic regulation The role of the carnitine pool in regulating epigenetic processes helps to reveal the deep link between cellular metabolism and epigenetic regulation

These salts are then secreted into bile and kept in the gallbladder until released into the small intestine, emulsifying fats and creating micelles that enterocytes can absorb (91)