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The c-MYC/NAMPT/SIRT1 feedback loop is activated in early classical and serrated route colorectal cancer and represents a therapeutic target

For clarification, oral administration of glucocorticoids also includes oromucosal, buccal, gingival and sublingual routes

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These engineered MSC-Exos inhibited ferroptosis and fibrosis in lung epithelial cells by inhibiting SMAD2, a key protein in TGF- signaling, and Akt, a protein involved in cell survival and growth