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doi:10.1038/s41596-021-00622-1 181

doi: 10.3389/fphar.2025.1560567 Received 14 January 2025 Accepted 28 March 2025 Published 16 April 2025 Volume 16 - 2025 Edited by Duuamene Nyimanu, University of Kansas Medical Center, United States Reviewed by Hao Du, Yale University, United States Ashish Dhayani, University of Pittsburgh, United States Updates Copyright 2025 Zhao, Jin, Zhao, Wang, Zhao, Xue, Qiao, Qu, Han and Tao

Lipid peroxidation Lipid peroxidation, a critical mechanism in ferroptosis, is a procedure in which oxidizing agents, like free radicals, target lipids that possess carboncarbon double bonds, particularly in PUFAs [100103]

hence, they could be part of the mechanism that leads to hypertension
Furthermore, the market needs to focus on product safety issues which encompass ingredient transparency and the potential for negative effects

if the overdose is spread over a period of time the threshold may be higher, as the initial paracetamol dose is effectively metabolized
