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Glutaric aciduria

In the TMLHE gene knockout mouse model, the carnitine biosynthetic pathway is inhibited due to the loss of TMLD activity in the liver, affecting the availability of carnitine in the heart, significantly reducing the rate of synthesis of LCACs, and contributing to the protection of mitochondrial function after myocardial IRI [215]

Effect of L-carnitine administration to pregnant mice on some reproductive hormones and organs

[DOI] [PubMed] [Google Scholar] 52.Dupuis L, Oudart H, Ren F, Gonzalez de Aguilar JL, Loeffler JP

doi:10.1002/mrd.23542