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Free Radical Biol Med 21:9951000 Dringen R, Pfeiffer B, Hamprecht B (1999) Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

Half-maximal inhibitory concentration values for 63 hypersensitive sites were measured

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This is a standard ratio used to keep math simple while maintaining stability

Note that reconstituted injectable GHK-Cu can be used topically, but topical copper peptide products formulated for skin application may include additional ingredients optimizing penetration and stability that simple water reconstitution doesn't provide

An additional experiment conducted during this study showed that by treating 3T3-L1 adipocytes with NAC (600 M), a methylglyoxal impairment in insulin signalling was relieved, as shown by decreased insulin-induced insulin receptor substrate-1 tyrosine phosphorylation and decreased activity of phosphatidylinositol 3-kinase (66)