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Long-term weight maintenance typically requires ongoing treatment or aggressive lifestyle modifications that most people find difficult to sustain

Targeting approaches to the HGF/Met signaling axis is mostly comprised of mAbs (directed against Met or HGF), tyrosine kinase inhibitors (TKI), and/or a NK4 decoy, which is a HGF antagonist (18)

E2F6, E2F7, and E2F8 are members of the E2F family of TF, which play important roles in cell cycle regulation, cell proliferation and survival, and gene expression 57

J Auton Nerv Syst 44: 129136, 1993