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Mild hypothermia has been demonstrated to significantly reduce the rate of DGF among recipients: in a randomized clinical trial including 394 donors randomized to mild hypothermia (34-35C) or normothermia (36.5 to 37.5C), DGF occurred in 79 recipients (28%) in the hypothermia group and in 112 recipients (39%) in the normothermia group (OR 0.62, 95%CI 0.43 to 0.92, p=0.02) (131)

Furthermore, Treg cellspecific VHL deficiency increases HIF-1-dependent glycolysis and impairs suppressive function in vivo (95)

[36] extracted glutathione from fat-removed and crushed corn embryos by using ultrasound to breakdown cell walls, followed by extraction at 90 C for 20 min

doi: 10.1007/s11033-011-1292-

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Perera, N., Rudland, V