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Both Hes1 and Hey1 are understood to promote G1-S transition by transcriptionally repressing p21 in a bHLH domain-dependent manner [52]
Figure 3A )
doi: 10.1016/j.jare.2020.06.013
Zhu M, Wang H, Chen J, Zhu H
ACS Biomater Sci Eng 11:25282549
Levels of reduced and oxidized coenzymeQ-10 and 8-hydroxy-2-deoxyguanosine in the cerebrospinal fluid of patients with living parkinsons disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process
