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A recent study in Caenorhabditis elegans revealed that early-life B12 deficiency caused increase in the levels of fat and demonstrated that the methionine cycle-SBP- 1/SREBP1-lipogenesis axis was required for early-life B12 to determine health outcomes later in life [30]

In addition, higher concentrations of biochar particles and DOM may inhibit the removal of the compound through the interactions between DOMs and the analyte 33,38 )

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While folic acid is the key preventive measure for neural tube defects, ensuring adequate B12 status is also important for overall maternal and foetal health

Obesity 31 , 111122 (2023)

Gastrointest Endosc