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These patients, who collectively account for 25-30 percent of all people with major depression disorder, are precisely the ones most in need of effective pharmacological interventions, says Rasgon, who performed the bulk of the advanced data analysis for the study

Additional information Competing interests The authors declare that they have no competing interests

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One meta-analysis indicated that berberine was better than a placebo at lowering blood sugar

LXR regulates cholesterol uptake through idol-dependent ubiquitination of the LDL receptor