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If pregnant, the NHS advises limiting oily fish to no more than 2 portions per week and avoiding shark, swordfish, and marlin due to mercury content

Thus, while the results of this study cannot definitively explain the lack of power output enhancement with long-term intake of GPLC, the limited information available suggests that excessive localized muscle pumping is involved

doi:10.1016/j.jpainsymman.2011.02.006

according to Dinca et al

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This offers a clear, mechanistic explanation for why so many dysautonomia patients report improved orthostatic tolerance and reduced tachycardia when incorporating mitochondrial shuttles into their daily treatment protocols