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2021;896 doi: 10.1016/j.ejphar.2021.173913

Numerous current clinical investigations are restricted by limited sample sizes, abbreviated follow-up durations, and methodological discrepancies

A key limitation in the field is that only blood and faecal samples are available, and, as discussed above, the current biomarkers for intestinal permeability are not reliable enough to answer this question

First, academia should foster an environment conducive to the early stages of translation by determining clinical needs, assembling interdisciplinary teams, reforming academic promotion systems, collaborating with technology transfer offices and establishing regional translation centers