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This creates a cascade of inflammation that affects multiple systems, leading to debilitating symptoms that often masquerade as other diseases

(2020) The biology of ergothioneine, an antioxidant nutraceutical

This study reports on the generation of an MOR-Cre knock-in mouse, enabling precise genetic access to MOR-expressing neurons, preserving receptor function and enabling circuit mapping and manipulation of opioid-responsive pathways underlying analgesia and addiction

A critical gap is the identification of definitive molecular switches that determine whether the crosstalk promotes tumor cell survival or death in a given therapeutic setting, which severely impedes the rational design of pathway-specific modulators

Pharm (Basel) 15

doi: 10.1016/j.expneurol.2011.02.019