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Were not just trying to put out a fire

Accordingly, it has issued new advice to check vitamin B12 serum levels in patients being treated with metformin who have symptoms suggestive of vitamin B12 deficiency.[] The proposed mechanisms to explain metformin-induced vitamin B12 deficiency among patients with T2DM include alterations in small bowel motility, which stimulates bacterial overgrowth and consequential vitamin B12 deficiency, competitive inhibition or inactivation of vitamin B12 absorption, alterations in IF levels, and interaction with the cubulin endocytic receptor

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Nature-inspired and medicinally relevant short peptides

In BSNC-1.0, synergistic B, N, S doping stabilized the carbon framework, achieving nearly 100% capacity retention after 10,000 cycles 99

J Pharmacol Sci 2007