enzyme glutathione peroxidase 1 GPX1 and Its Dichotomous Roles in Cancer The glutathione peroxidase family: Discoveries

There are several different versions of GPx, each adapted to a different cellular compartment or tissue context GPx1 in the cytosol, GPx2 in the gastrointestinal tract, GPx3 in plasma, GPx4 in membranes

Enhanced expression of GPx2 is associated with growth, metastasis, and a low survival rate in oncologic patients (Peng et al

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An additional feature of the mammalian mechanism is the presence of a selenocysteine residue at the C-terminal end of the protein which is required for catalytic activity

Barbonetti, A

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