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Description

Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis

As protein carbonylation is irreversible and cellular enzymes are unable to repair such oxidative damage, carbonylated proteins are degraded by the cell's proteasomal system (Baraibar and Friguet 2012)

[DOI] [Google Scholar] 72.Grasser E.K., Miles-Chan J.L., Charrire N., Loonam C.R., Dulloo A.G., Montani J.P

Banihani S, Agarwal A, Sharma R, Bayachou M

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