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Brain Res 1214:177187 Lv L, Yang F, Li H, Yuan J (2020) Brain-targeted co-delivery of -amyloid converting enzyme 1 shRNA and epigallocatechin-3-gallate by multifunctional nanocarriers for Alzheimers disease treatment

Unlike enzyme induction, which requires multiple doses of the interacting drug to develop, enzyme inhibition occurs immediately after the first administration of the inhibiting drug, as it directly blocks the enzymes activity without needing time for upregulation or synthesis

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[DOI] [PubMed] [Google Scholar] 18.Hu X., et al

Curcumin is a recognized pleiotropic compound with ability to interact with various pro-inflammatory molecules secreted during inflammation process (Fig