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furthermore, in the damaged brain region, new neurons differentiated from NSCs can integrate into functional neural loops and repair damaged nerves ( Molecular mechanisms involved in endogenous neurogenesis after neonatal HIBD HIF-1 Hypoxia-inducible factor (HIF-1) is a major transcriptional activator induced by hypoxia and ischemia

Many short-term intervention studies in older individuals with vascular diseases have found that therapeutic doses of citicoline given orally, by intramuscular injection, or by intravenous infusion resulted in improvements in neuropsychological functions, including cognitive, emotional, and behavioral functions (reviewed in 5)

This capability supports the development of personalized protocols, improving efficacy while minimizing side effects [231, 235, 236]

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Epithalon helps slow this process by activating telomerase , a key enzyme involved in cellular longevity

Down-regulation of microRNA-142-5p attenuates oxygen-glucose deprivation and reoxygenation-induced neuron injury through up-regulating Nrf2/ARE signaling pathway