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B12 does wonders inside the body, but its benefits can also be seen on the outside as well

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Greying or Whitening of Hair: The premature greying of hair may be associated with low B12 or D

One review concluded that vitamin B12 plays a key role in fat metabolism, noting that a deficiency could be linked to increased fat accumulation and obesity ( Another animal study found that severe vitamin B12 deficiency led to a significant increase in body fat percentage and cholesterol levels in pregnant mice ( Whats more, one animal study showed that administering B vitamins to rats fed a high fat diet reduced weight gain and increased levels of several enzymes that influence metabolism, compared with a control group ( However, current evidence is lacking, and additional high quality studies are needed to determine how vitamin B12 may affect metabolism and body fat in humans

Various inherited defects in the synthesis of the biologically active forms of vitamin B12 (ie, adenosylcobalamin and methylcobalamin) from ingested cobalamin substrate are referred to as cobalamin defects or diseases A-H

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