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242,479 The aging process is proven to be accompanied by inhibited AMPK pathway, as well as decreased physical fitness and mitochondrial fragmentation

Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae

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GDF11 alleviates secondary brain injury after intracerebral hemorrhage via attenuating mitochondrial dynamic abnormality and dysfunction