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Probes are listed in Supplementary Table 3

The most common form of HH is caused by mutations in the HFE gene, with most cases of HH presenting in patients who are homozygous for the Cys282Tyr mutation

The CD8 + T cells were cultured and expanded in T cell media, which comprised RPMI 1640 supplemented with 10% fetal bovine serum, 20 mM HEPES, 1 mM sodium pyruvate, 0.05 mM 2-mercaptoethanol, 2 mM L-glutamine, 100 U/mL streptomycin, and 100 mg/mL penicillin, along with 20 ng/mL of recombinant mouse IL-2 (BioLegend, Cat# 575406)

812, www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/
AAUCD: Plasma Amino Acids, Urea Cycle Disorders Panel

Inflammation increases during manic episodes and decreases during depressive episodes (Modabbernia et al., 2013