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Description
CYP2E1 has been implicated in hepatotoxicity induced by alcohol metabolism and exogenous toxicants, playing a central role in nonalcoholic steatohepatitis and other liver diseases [3,4,5,6]

Glycogen breakdown is regulated by 3,5-cyclic adenosine monophosphate (cAMP) and Ca 2+ , and supports astrocytic potassium and glutamate uptake and glutamine synthesis

On the other hand, despite the widespread use of in vivo animal models in IRI research, significant translational challenges hinder the extrapolation of preclinical findings to human patients

Rajani et al

46 Biologics such as antivascular endothelial growth factor (anti-VEGF) therapy have also been demonstrated to increase tumor oxygenation

SjgrenKLiuJBladKSkrticSVidalOWalleniusVet al