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For example, neural cell adhesion molecule (NCAM) is a membrane-bound glycoprotein that is specifically expressed throughout the nervous system and facilitates adhesion and interconnection between neurons by forming a highly adherent meshwork on the cell surface via a transmembrane structure dependent on numerous fine membrane numbers [79]

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Notably, in co-culture systems with endothelial cells, astrocytes have been demonstrated to induce the transdifferentiation of non-neurovascular endothelial cells into a brain-specific phenotype, thereby giving them BBB-like characteristics (Hayashi et al., 1997)

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Bag Filter Maintenance and Replacement When to Replace Bag Filters Replace bag filters when differential pressure across the housing reaches the manufacturers recommended maximum, typically 1.5 to 2.5 bar (20 to 35 PSI)

[5] Alba et al