glutathione gene mutation Inborn errors in the metabolism of | Orphanet Journal of Rare Diseases Early genetic diagnosis of glutathione

While anecdotal reports are widespread, formal human clinical trials are limited

139 not only achieved a retardation of tumor growth but in 36% of cases a complete remission of benzo()pyren-induced cutaneous squamous cell carcinomas

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Since GSH is not carried inside the cell, exogenously administered GSH is most likely to act by increasing plasma GSH levels reducing luminal oxidative stress and increasing NO bioavailability in patients with endothelial dysfunction (220)

Moreover, most preclinical models evaluating the analgesic effects of peptides do not involve wounds as the primary source of nociception

Of those, five are most-cited in primary literature