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5,6,10,11,17,18,21 Melanoma is also refractory to most systemic chemotherapies

[11] A small amount of black eumelanin in the absence of other pigments causes grey hair
[DOI] [PMC free article] [PubMed] [Google Scholar] Kobayashi T., Kawai H., Suzuki T., Kawanishi T., Hayakawa T

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However, these drugs differ in a few key areas worth considering when choosing the best first-line option for a particular patient
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