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As a result, various inhibitors have been developed

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Daily dosing would risk supratherapeutic accumulation and is not supported by the published pharmacokinetic data

Two of them reported no statistically significant results (i.e., NTC03216954 and NTC02791945), whereas another study provided evidence of a reduction in heavy drinking days but for both the group treated with NAC and the placebo (i.e., NTC00568087)

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