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doi: 10.1016/j.anifeedsci.2014.06.010 157 SilveiraS

MK-677, a mimetic HGH-releasing peptide administered in older individuals enhanced pulsatile HGH release, increased serum HGH and IGF-I levels, and at a dose of 25 mg/day even restored serum IGF-I concentration (Chapman et al., 1996)

doi: 10.1159/000109343

NICE recommends lifestyle modifications and PDE5 inhibitors such as sildenafil, tadalafil, vardenafil, and avanafil as first-line pharmacological treatments
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IGF-1 is a hormone produced primarily in the liver in response to growth hormone (GH) secretion from the pituitary gland

Eur J Clin Pharmacol 80:110
