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The secretion of the pro-inflammatory cytokine TNF- increases with age, and studies have confirmed that TNF- significantly inhibits the activity of Toll-like receptor-2 (TLR2) and TLR4

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The Hinge peptide (KDYIRN), which represents the dimerization domain of HGF, was included as a positive control

For patients waiting for access to physician-prescribed peptide protocols, the trajectory is clear

J Asthma 2015

Although the small sample size of the more recent studies could have reduced their statistical power, current data regarding benefits of HP eradication remain controversial
