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Ethics statement The studies involving humans were approved by Research Ethics Committee, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

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The peptide releases directly into the gastric environment where it can exert local protective effects before degradation occurs

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The researchers used a powerful molecule called bone morphogenetic protein 2 (BMP2) to initiate bone formation after microfracture, but then stopped the process midway with a molecule that blocked another signaling molecule important in bone formation, called vascular endothelial growth factor (VEGF)