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Although this study suggests that there are differences in serum copper concentrations among bipolar disorder patients at different stages of the disease, these differences did not reach statistical significance (Siwek et al., 2017)

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This term is now defined as the imbalance between cellular pro-oxidant levels and antioxidant capacity in favor of the former (30, 52, 87), implying that an excess in oxidant levels leads to oxidative stress (Fig

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In summary, plantderived bioactive compounds have gained momentum as potential alternatives or adjuncts to levodopa, owing to their multipronged neuroprotective effects

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Pathological conditions can further influence excretion

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