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Supplementary Figure 2 Modularity vs

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The electron transport chain (ETC) regulates ferroptosis Mitochondrial ETC activity is not only essential for ATP production but is also required for the generation of sufficient lipid ROS to initiate ferroptosis

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P.et al (2016a)

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Recent studies suggest that lipid peroxidation might create gaps in the plasma membrane, disrupting ionic homeostasis and leading to ferroptotic death without immediate rupture [70]

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