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2.3 Species relevance Chemicals were selected based on high relevance to humans, wherever possible
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J Pharmacol Exp Ther 285:651658 [PubMed] [Google Scholar] Roche JP, Bounds S, Brown S, Mackie K 1999 A mutation in the second transmembrane region of the CB1 receptor selectively disrupts G protein signaling and prevents receptor internalization
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