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doi: 10.1016/j.jtos.2017.05.008 301 JonesLDownieLEKorbDBenitez-Del-CastilloJMDanaRDengSXet al

Microneedles have very small dimensions ranging from hundred microns in diameter, from units to tens of microns in size of tip and length of 252000 m

The polymeric core is composed of generation 4.0 polyamidoamine dendrimer (G4 PAMAM or G4), which can accommodate both lipid-soluble drugs (Siv) and water-soluble drugs (PMB) within its internal cavities

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Tomaniak M, Katagiri Y, Modolo R, de Silva R, Khamis RY, Bourantas CV, et al

Impairment of this system leads to myocardial edema and functional deterioration ( Therefore, enhancing cardiac lymphatic function may emerge as a novel therapeutic strategy