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3.2.3 Application of PCLS to study cell death pathways Various cell death pathways have been observed in lung IRI, including apoptosis, necrosis, pyroptosis and ferroptosis ( 4 Summary, limitations and future perspectives 4.1 Summary Lung IRI is the main risk factor for primary graft dysfunction and mortality following LTx

This review serves as a valuable resource for researchers aiming to develop new formulations, yet future studies must prioritize rigorous pharmacokinetic evaluations and long-term toxicity profiles to ensure patient safety

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The purpose of this paper is to introduce the PEI as an appropriate vector for the effective gene delivery

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