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The key difference between the MALDI and ESI ionization sources lies in the former producing low-charge ions (mono and doubly-charged), which simplifies molecular mass determination for most biomolecules and makes data interpretation easier compared to ESI-MS

: L-carnitine , : L-carnitine

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It is unlikely to cause significant weight loss

However, it is possible that nhr-49 controls fatty acid -oxidation and desaturation through an indirect mechanism, functioning upstream of the transcription factors that directly act on the nhr-49 -dependent genes identified in this study

the color may vary from shades of dark brown to black The macules may be single or multiple