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Dailleurs, les personnes prsentant un dficit primaire en L-carnitine sont plus susceptibles dtre atteintes de troubles hpatiques, suggrant un rle cl de la L-carnitine dans la sant du foie

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In addition, the monomethyl branched-chain fatty acid C17iso could ensure the integrity of the ER membrane, whose biosynthesis requires the acyl coenzyme A synthase encoded by fatty acid CoA synthetase-1 ( acs-1 ), thereby maintaining the function of ER-resident enzymes for an appropriate lipid synthesis and the growth of LDs [46]

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Routine lab monitoring may also be a helpful marker of compliance when a carnitine supplement, such as levocarnitine, is prescribed and it can help clinicians adjust the prescription to optimize serum levels