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Positive feedback loops that amplify OxS over long intervals can eventually result in irreversible OxS-driven micro- and macro-vascular damage

Variations in the CYP1A gene place each of us in one of two groups: "fast" metabolizers vs "slow" metabolizers

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They also reported that the cytoprotective and ROS-reducing effects of ERW were abolished by degassing but not by neutralizing the pH, confirming that H 2 , not the pH or alkalinity, is responsible for the therapeutic effects of ERW [133]