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Solutions All solutions used in the perfusion of isolated cells or whole hearts were based on modified Tyrodes solution, as used in our previous publications (Brennan et al., 2024

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AX has been shown to buffer mitochondrial overload, which can be induced by physical exercise, as exercise inherently promotes ROS formation and mobilizes fuels within the mitochondria, but also by an HFD, as observed in obesity, which continuously stimulates the mitochondrial network in ATP production, fatty acid synthesis, and the consequent generation of ROS (Figure 2) [4,46]

Vigabatrin is a selective, irreversible inhibitor of GABA-transaminase, the enzyme that degrades GABA, thereby increasing GABA levels in the CNS

Eyes: HSV keratitis, an infection in your cornea, can cause blindness