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Summary: Low B12 commonly causes neurological symptoms (pins and needles, balance problems, memory issues) and haematological features (fatigue, breathlessness, sore tongue), which may develop gradually over months

The Cu/Zn superoxide dismutase+ 35A/C (rs2234694) variant correlates with altered levels of protein carbonyls and glutathione and associates with severity of COPD in a Tunisian population

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Higher levels of ROS can trigger peripheral and central nervous system hyperexcitability that can lead to hyperalgesia, even without nerve damage or tissue inflammation (Hendrix et al., 2020)

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Seizure , 16 (1), 6973