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*The dyes tartrazine and sunset blue FCF may have an adverse effect on activity and attention in children

Despite interest in LCs metabolic role, little is known about how dosing strategyparticularly split versus single-dose intakemight influence performance outcomes

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The treatment of mice with daidzein and genistein (low dose 20 mg/kg or high dose 150200 mg/kg) for two weeks reversed the polyinosinic:polycytidylic acid [poly(I:C)]-induced decrease in locomotor activity and brain/skin gene expression, as well as serum levels of pro-inflammatory mediators relevant to CFS (i.e., TNF-, IL-6, keratinocytes-derived chemokine (IL-8/(CXC motif) ligand (CXC)L8 murine homolog), chemokine (CC motif) ligand-2, -4, -5 (CCL2, CCL4, CCL5) and C-X-C motif chemokine ligand 10 (CXCL10))

Greenhouse-Geisser group (G), time (T), and group x time (G x T) interaction p-levels are reported with univariate treatment p-levels

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