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For instance, Pelleri et al

Blood acetaldehyde levels were 2- to 3.2-fold higher in ALDH2 knockout mice compared with wild-type mice, when measured after 4 h of inhaling acetaldehyde at a concentration of 5,000 ppm

Cellular alterations include increased lipid peroxides, elevated reactive oxygen species (ROS), and reduced Glutathione Peroxidase 4 (GPX4) levels (Song Y

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