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Nucleoside-analog reverse transcriptase inhibitors such as adefovir dipivoxil are well known for their mitochondrial toxicity and may be involved in HIV-associated neurodegeneration and other accelerated aging phenotypes ( Statements Data availability statement The original contributions presented in the study are included in the article/Supplementary Material, further inquiries can be directed to the corresponding authors

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PATHOPHYSIOLOGY OF ATHEROSCLEROSIS Atherosclerosis in Cardiovascular Disease As the underlying cause of heart attack, stroke, and peripheral vascular disease, atherosclerosis is the major cause of death and morbidity in the United States and the industrial world (1)