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Trx1(SH) 2 catalyzes denitrosylation of caspase3 nitrosylated at Cys163, whereas Trx1SNO prevents apoptosis by transnitrosylating caspase3 at the same cysteine residue and induces oncogenic cell transformation [134, 136-138]
112 Islet cells shift from a compensatory increase to reduced function and decreased cell mass
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