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The suggestion that carnitine deficiency may lead to frailty through mitochondrial dysfunction (117) has been examined in one trial

doi: 10.1210/me.2009-0402 93 MaseroliEComeglioPCornoCCellaiIFilippiSMelloTet al

Leptin regulates bone formation via the sympathetic nervous system

Other studies have also shown that mice that knock out the IL-10 gene are a good model of inflammatory bowel disease

Acetyl-L-Carnitine plays an essential role in fatty acid metabolism, helping to transport long-chain fatty acids across cellular membranes and into the mitochondria to be used in the production of energy

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