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Targeting CD44 by CRISPR-Cas9 in Multi-Drug Resistant Osteosarcoma Cells

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It may also suppress mitogen-activated protein kinase (MAPK) pathways, including ERK1/2, c-Jun N-terminal kinases (JNK), and p38 MAPK, attenuating the expression of inflammatory mediators and cytokines

Diabetes 2009;58:773-95.PubMedPMC 4

The presence of a variation in ERCC2 gene (rs13181 and rs1799793) reduces repair capacity, and results in greater efficacy of cisplatin treatment due to increased DNA damage and an enhanced cytotoxic effect

13,6,7 The initial laboratory assessment of a patient with suspected vitamin B 12 deficiency should include a complete blood count and a serum vitamin B 12 level