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They include microangiopathy with endoneurial hypoxia, excessive oxidative stress with overproduction of harmful reactive oxygen species, defects in macrophage function and inflammatory repair, reduced regenerative activity on the part of Schwann cells and impaired neuronal cell body response caused by deficient neurotrophic support [5]

doi: 10.1111/j.1440-1746.2008.05310.x

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Park DJ, Kang JH, Yim YR, Kim JE, Lee JW, Lee KE, Wen L, Kim TJ, Park YW, Lee SS